heat shock factor binding protein 1 pseudogene 1Genealiases: []
Q-omics provides the consensus-scored HSBP1P1 profile across patient tissues and cancer cell-line models. HSBP1P1 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, HSBP1P1 is differentially expressed in 4, with the highest sampling consensus in KIRC. Additionally, HSBP1P1 RNA expression shows 7,196 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight MESO, KIRC, and GBM as cancer lineages where HSBP1P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for HSBP1P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes HSBP1P1 survival associations across molecular data types. HSBP1P1 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible HSBP1P1 RNA expression–survival associations across cancer types. High HSBP1P1 expression shows unfavorable associations in MESO, ACC, UVM and KIRP, but favorable associations in ESCA and COAD. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for HSBP1P1 RNA expression.
This table summarizes HSBP1P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for HSBP1P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. HSBP1P1 shows lower tumor expression in THCA and higher tumor expression in KIRC, COAD and LUAD. The KIRC box plot shows higher HSBP1P1 RNA expression in tumor versus normal tissue (log2 FC = +0.060, t-test p = .018).
This table shows molecular features associated with HSBP1P1 in patient tissues and cancer cell lines. In patient samples, HSBP1P1 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
