OPALIN

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OPALIN RNA expression is significantly associated with the protein abundance of many other proteins, with 12,977 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OPALIN-associated proteins across cancer lineages are GGA3, GGA3_S159, and BASP1. Each is linked with OPALIN in more than 1 cancer types. Because this analysis shows association rather than direction, both OPALIN-to-partner and partner-to-OPALIN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OPALIN→partner) and Y-score (partner→OPALIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMGGA3 →+0.208+1.392<.001<.00132
GBMGGA3_S159 →+0.310+1.776<.001<.00132
GBMBASP1 →+0.932+2.080<.001<.00132
GBMBASP1_T36 →+0.737+1.745<.001<.00132
GBMBCL6_S457 →-0.682-1.647<.001<.00132
GBMCHN1 →+0.306+1.577<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,977 associations by consensus.

Exploration