OOSP2

Across TCGA patient cohorts, OOSP2 mutation is significantly associated with the RNA expression of many other genes, with 762 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OOSP2-associated genes across cancer lineages are UFD1, CDC45, and H2AB2. Each is linked with OOSP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OOSP2-to-partner and partner-to-OOSP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UFD1 grouped by OOSP2-low versus OOSP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OOSP2→partner) and Y-score (partner→OOSP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UFD1 →	+0.577	+3.513	<.001	.002	3	3
UCEC	CDC45 →	+1.022	+3.513	<.001	.002	3	3
BRCA	H2AB2 →	+0.067	+7.473	<.001	.007	3	2
UCEC	TATDN2 →	+0.519	+3.480	<.001	.002	3	2
UCEC	CCNB2 →	+0.984	+3.459	.001	.005	3	2
UCEC	BAP1 →	+0.424	+3.459	.006	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 762 associations by consensus.

UFD1 by OOSP2 expression — UCEC

Explore this box plot interactively →