OOEP-AS1

Across TCGA patient cohorts, OOEP-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,747 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OOEP-AS1-associated GO terms across cancer lineages are Regulation of RNA splicing, Cytoskeleton-dependent intracellular transport, and Regulation of DNA-templated transcription elongation. Each is linked with OOEP-AS1 in more than 17 cancer types. Because this analysis shows association rather than direction, both OOEP-AS1-to-partner and partner-to-OOEP-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by OOEP-AS1-low versus OOEP-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OOEP-AS1→partner) and Y-score (partner→OOEP-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of RNA splicing →	+0.076	+0.320	<.001	<.001	3	18
STAD	Cytoskeleton-dependent intracellular transport →	+0.045	+0.219	<.001	<.001	3	17
STAD	Regulation of DNA-templated transcription elongation →	+0.059	+0.240	<.001	<.001	3	16
ESCA	Spindle assembly →	+0.074	+0.342	<.001	<.001	3	16
ESCA	Obsolete ncRNA catabolic process →	+0.066	+0.342	<.001	<.001	3	16
ESCA	Peptidyl-lysine modification →	+0.066	+0.329	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,747 associations by consensus.

Regulation of RNA splicing by OOEP-AS1 expression — ESCA

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