OLFML3

Across TCGA patient cohorts, OLFML3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,596 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible OLFML3-associated genes across cancer lineages are SMOC2, C7, and DCN. Each is linked with OLFML3 in more than 9 cancer types. Because this analysis shows association rather than direction, both OLFML3-to-partner and partner-to-OLFML3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OLFML3 versus SMOC2 in CCRCC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLFML3→partner) and Y-score (partner→OLFML3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SMOC2 →	+1.397	+0.591	<.001	<.001	3	10
OV	C7 →	+2.296	+0.776	<.001	<.001	3	10
CCRCC	DCN →	+2.149	+0.611	<.001	<.001	3	10
BRCA	EBF1 →	+0.921	+0.783	<.001	<.001	3	10
BRCA	CD34 →	+0.807	+0.865	<.001	<.001	3	10
BRCA	MSRB3 →	+1.492	+0.931	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,596 associations by consensus.

OLFML3 vs SMOC2 — CCRCC

Explore this scatter interactively →