OLFML3

Across TCGA patient cohorts, OLFML3 protein abundance is significantly associated with the protein abundance of many other proteins, with 35,321 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OLFML3-associated proteins across cancer lineages are NID2, OGN, and OLFML1. Each is linked with OLFML3 in more than 9 cancer types. Because this analysis shows association rather than direction, both OLFML3-to-partner and partner-to-OLFML3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OLFML3 versus NID2 in GBM, with a Pearson correlation of 0.70.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OLFML3→partner) and Y-score (partner→OLFML3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NID2 →	+0.699	+0.782	<.001	<.001	3	10
UCEC	OGN →	+1.409	+1.113	<.001	<.001	3	10
UCEC	OLFML1 →	+1.495	+1.193	<.001	<.001	3	10
UCEC	ARHGEF17 →	+0.469	+0.972	<.001	<.001	3	10
BRCA	DCN →	+1.400	+1.261	<.001	<.001	3	10
UCEC	DPT →	+0.954	+0.932	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 35,321 associations by consensus.

OLFML3 vs NID2 — GBM

Explore this scatter interactively →