OLFML3

Across TCGA cell cohorts, OLFML3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,840 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OLFML3-associated GO terms across cancer lineages are Collagen biosynthetic process, Melanocyte proliferation, and Regulation of calcineurin-mediated signaling. Each is linked with OLFML3 in more than 6 cancer types. Because this analysis shows association rather than direction, both OLFML3-to-partner and partner-to-OLFML3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Collagen biosynthetic process grouped by OLFML3-low versus OLFML3-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OLFML3→partner) and Y-score (partner→OLFML3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Collagen biosynthetic process →	+0.155	+1.850	<.001	<.001	3	7
SKIN	Melanocyte proliferation →	+0.939	+2.487	<.001	<.001	3	7
SOFT_TISSUE	Regulation of calcineurin-mediated signaling →	+0.118	+2.279	<.001	<.001	3	6
SKIN	Response to amyloid-beta →	+0.096	+2.282	<.001	<.001	3	6
OVARY	Cellular response to amyloid-beta →	+0.098	+1.620	.002	.001	3	6
SOFT_TISSUE	Negative regulation of intrinsic apoptotic signaling pathway →	+0.078	+2.660	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,840 associations by consensus.

Collagen biosynthetic process by OLFML3 expression — CNS

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