OLFML2B

Across TCGA cell cohorts, OLFML2B mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OLFML2B-associated genes across cancer lineages are C2orf80, C6orf118, and ACER1. Each is linked with OLFML2B in more than 1 cancer types. Because this analysis shows association rather than direction, both OLFML2B-to-partner and partner-to-OLFML2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C2orf80 grouped by OLFML2B-low versus OLFML2B-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLFML2B→partner) and Y-score (partner→OLFML2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	C2orf80 →	+0.130	+4.199	<.001	.007	3	1
LARGE_INTESTINE	C6orf118 →	+0.130	+3.115	<.001	.004	3	1
LARGE_INTESTINE	ACER1 →	+0.082	+3.145	.001	.004	3	1
SKIN	CEACAM8 →	+0.007	+3.632	<.001	.003	3	1
SKIN	PRL →	+0.359	+3.819	<.001	.003	3	1
SKIN	OR10H5 →	+0.011	+3.977	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

C2orf80 by OLFML2B expression — BREAST

Explore this box plot interactively →