Across TCGA cell cohorts, OLFML2A mutation is significantly associated with the RNA expression of many other genes, with 47 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OLFML2A-associated genes across cancer lineages are RAB19, AQP8, and MYOM3. Each is linked with OLFML2A in more than 1 cancer types. Because this analysis shows association rather than direction, both OLFML2A-to-partner and partner-to-OLFML2A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLFML2A→partner) and Y-score (partner→OLFML2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RAB19 →	+0.393	+3.379	.006	.006	3	2
BLOOD_Leukemia	AQP8 →	+0.100	+3.697	<.001	.002	3	1
BLOOD_Leukemia	MYOM3 →	+0.064	+4.106	<.001	.003	3	1
BLOOD_Leukemia	PRND →	+0.004	+3.289	.004	.002	3	1
BLOOD_Leukemia	WFIKKN2 →	+0.009	+3.632	.004	.003	3	1
BLOOD_Leukemia	TBC1D28 →	+0.047	+3.189	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

Exploration

OLFML2A survival (RNA) · tumor vs normal (RNA) · all OLFML2A data types