OLFM3

Across TCGA cell cohorts, OLFM3 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OLFM3-associated genes across cancer lineages are PRR20C, KLRF2, and SOX14. Each is linked with OLFM3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OLFM3-to-partner and partner-to-OLFM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRR20C grouped by OLFM3-low versus OLFM3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLFM3→partner) and Y-score (partner→OLFM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PRR20C →	+0.032	+3.201	<.001	.004	3	2
LUNG_NSCLC_LUSC	KLRF2 →	+0.193	+4.643	<.001	.008	3	1
OESOPHAGUS	SOX14 →	+0.367	+4.392	<.001	.003	3	1
LUNG_SCLC	OR6F1 →	+0.068	+3.817	<.001	.004	3	1
LUNG_SCLC	BLID →	+0.063	+3.523	<.001	.008	3	1
LUNG_NSCLC_LUAD	LILRA1 →	+0.017	+3.043	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

PRR20C by OLFM3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →