OLFM1

Across TCGA pan-cancer cohorts, OLFM1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated OLFM1 data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher OLFM1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated OLFM1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and GBM show a favorable association.

PDAC, LUAD, and GBM are the cancer types where OLFM1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	All	0.259	0.701	.003	32	view →
LUAD	DFS	Quartile	II,III,IV	1.000	0.289	.022	5	view →
GBM	OS	Quartile	All	0.904	0.758	.037	1	view →
HNSC	OS	Quartile	II,III,IV	0.724	1.000	.048	1	view →
LSCC	DFS	Tertile	All	0.848	1.000	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

OLFM1–PDAC (OS)

Open the PDAC breakdown →