OLFM1

Across TCGA patient cohorts, OLFM1 mutation is significantly associated with the RNA expression of many other genes, with 5,396 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OLFM1-associated genes across cancer lineages are LINC00239, CHASERR, and SELENOS. Each is linked with OLFM1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OLFM1-to-partner and partner-to-OLFM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00239 grouped by OLFM1-low versus OLFM1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OLFM1→partner) and Y-score (partner→OLFM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC00239 →	+0.955	+3.247	<.001	<.001	3	3
UCEC	CHASERR →	+0.402	+1.469	.001	<.001	3	3
UCEC	SELENOS →	+0.454	+1.635	<.001	<.001	3	3
UCEC	ITGB3BP →	+0.357	+2.747	<.001	<.001	3	3
COAD	ZBTB8A →	+0.410	+3.753	<.001	<.001	3	3
UCEC	PIGA →	+0.396	+1.974	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,396 associations by consensus.

LINC00239 by OLFM1 expression — COAD

Explore this box plot interactively →