OGG1

Across TCGA patient cohorts, OGG1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,256 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OGG1-associated genes across cancer lineages are HBA2, ANO3, and BDNF-AS. Each is linked with OGG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OGG1-to-partner and partner-to-OGG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OGG1 versus HBA2 in BRCA, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OGG1→partner) and Y-score (partner→OGG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HBA2 →	+1.299	+0.397	.003	.001	3	2
GBM	ANO3 →	-0.919	-0.492	<.001	<.001	3	2
GBM	BDNF-AS →	-0.610	-0.648	.001	.003	3	2
LSCC	NCALD →	-0.525	-0.221	.006	.002	3	1
LSCC	TRIM2 →	-0.777	-0.219	.002	.003	3	1
LSCC	SOX6 →	-0.944	-0.262	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,256 associations by consensus.

OGG1 vs HBA2 — BRCA

Explore this scatter interactively →