OGFR-AS1

Across TCGA pan-cancer cohorts, OGFR-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated OGFR-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher OGFR-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OGFR-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and PAAD show a favorable association.

KIRC, BLCA, and LGG are the cancer types where OGFR-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.532	0.709	<.001	128	view →
BLCA	OS	Tertile	II,III,IV	0.766	0.620	.001	54	view →
LGG	DFS	Median	All	0.658	0.806	<.001	45	view →
PAAD	DFS	Tertile	II,III,IV	0.529	0.254	.003	40	view →
SKCM	OS	Median	IV	1.000	0.257	.001	38	view →
THCA	DFS	Quartile	II,III,IV	0.875	1.000	.003	29	view →
PRAD	DFS	Quartile	All	0.812	0.947	<.001	28	view →
BRCA	OS	Tertile	III,IV	0.963	0.842	.004	27	view →
ACC	DFS	Median	All	0.211	0.629	.001	24	view →
THYM	DFS	Median	II,III,IV	0.923	0.583	.004	21	view →
UCS	DFS	Tertile	IV	0.829	0.321	.024	18	view →
UVM	DFS	Quartile	III,IV	0.272	0.900	.006	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

OGFR-AS1–KIRC (DFS)

Open the KIRC breakdown →