OGFOD2

Across TCGA patient cohorts, OGFOD2 mutation is significantly associated with the RNA expression of many other genes, with 1,356 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OGFOD2-associated genes across cancer lineages are MRPS35P2, RN7SL248P, and RNU6-933P. Each is linked with OGFOD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OGFOD2-to-partner and partner-to-OGFOD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPS35P2 grouped by OGFOD2-low versus OGFOD2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OGFOD2→partner) and Y-score (partner→OGFOD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MRPS35P2 →	+0.159	+5.900	<.001	<.001	3	2
UCEC	RN7SL248P →	+0.048	+2.847	<.001	.008	3	2
COAD	RNU6-933P →	+0.790	+4.484	<.001	.002	3	2
COAD	RNU6-905P →	+0.271	+4.666	.007	.005	3	2
COAD	DPYD-AS2 →	+0.377	+4.374	.002	.002	3	2
COAD	RN7SL370P →	+0.614	+3.831	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,356 associations by consensus.

MRPS35P2 by OGFOD2 expression — SKCM

Explore this box plot interactively →