OGFOD1

Across TCGA patient cohorts, OGFOD1 mutation is significantly associated with the RNA expression of many other genes, with 1,114 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OGFOD1-associated genes across cancer lineages are JADRR, MIR6853, and MIR548AD. Each is linked with OGFOD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OGFOD1-to-partner and partner-to-OGFOD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JADRR grouped by OGFOD1-low versus OGFOD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OGFOD1→partner) and Y-score (partner→OGFOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JADRR →	+0.080	+2.976	.004	<.001	3	2
BRCA	MIR6853 →	+0.242	+8.057	<.001	.005	3	1
BRCA	MIR548AD →	+0.225	+7.471	<.001	.008	3	1
SKCM	RNU6-999P →	+0.444	+6.080	<.001	.002	3	1
SKCM	CACNA1C-IT1 →	+0.080	+5.097	<.001	.008	3	1
UCEC	TMEM238L →	+1.256	+3.917	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,114 associations by consensus.

JADRR by OGFOD1 expression — UCEC

Explore this box plot interactively →