Across TCGA patient cohorts, OGA mutation is significantly associated with the RNA expression of many other genes, with 2,085 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OGA-associated genes across cancer lineages are MIR498, BPY2DP, and MIR4440. Each is linked with OGA in more than 2 cancer types. Because this analysis shows association rather than direction, both OGA-to-partner and partner-to-OGA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OGA→partner) and Y-score (partner→OGA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR498 →	+0.180	+5.033	<.001	.003	3	3
STAD	BPY2DP →	+0.304	+5.105	<.001	.008	3	3
BLCA	MIR4440 →	+0.259	+4.314	<.001	.009	3	2
LUAD	LINC02283 →	+0.112	+6.333	<.001	<.001	3	2
COAD	MTCO3P16 →	+0.175	+4.893	<.001	.005	3	2
COAD	SEPTIN14P19 →	+0.089	+5.003	.003	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,085 associations by consensus.

Exploration

OGA survival (RNA) · tumor vs normal (RNA) · all OGA data types