OFD1

Across TCGA patient cohorts, OFD1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,697 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OFD1-associated genes across cancer lineages are CFAP70, RSPH1, and IQCK. Each is linked with OFD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both OFD1-to-partner and partner-to-OFD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OFD1 versus CFAP70 in UCEC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OFD1→partner) and Y-score (partner→OFD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CFAP70 →	+1.164	+0.232	<.001	.001	3	5
UCEC	RSPH1 →	+1.541	+0.202	<.001	<.001	3	5
OV	IQCK →	+0.610	+0.326	.001	.001	3	5
UCEC	TTLL9 →	+1.448	+0.320	<.001	<.001	3	4
BRCA	MFSD6L →	+0.941	+0.269	.002	.004	3	4
BRCA	NME5 →	+1.592	+0.418	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,697 associations by consensus.

OFD1 vs CFAP70 — UCEC

Explore this scatter interactively →