ODF3L1

Across TCGA patient cohorts, ODF3L1 mutation is significantly associated with the RNA expression of many other genes, with 1,336 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ODF3L1-associated genes across cancer lineages are RNU5B-6P, RNA5SP426, and RNU6ATAC29P. Each is linked with ODF3L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ODF3L1-to-partner and partner-to-ODF3L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU5B-6P grouped by ODF3L1-low versus ODF3L1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ODF3L1→partner) and Y-score (partner→ODF3L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU5B-6P →	+0.865	+7.741	<.001	.009	3	2
LUSC	RNA5SP426 →	+0.318	+7.924	<.001	.008	3	2
UCEC	RNU6ATAC29P →	+0.279	+2.289	.005	.004	3	2
COAD	RNU4-45P →	+0.538	+7.741	<.001	.009	3	2
SKCM	RNA5SP497 →	+0.418	+5.159	<.001	.007	3	1
SKCM	MIR3126 →	+0.484	+5.362	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,336 associations by consensus.

RNU5B-6P by ODF3L1 expression — COAD

Explore this box plot interactively →