ODF2L

Across TCGA pan-cancer cohorts, ODF2L mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ODF2L data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ODF2L mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ODF2L expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

HNSC, UCEC, and LSCC are the cancer types where ODF2L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	All	0.963	0.637	.019	10	view →
UCEC	DFS	Tertile	All	1.000	0.824	.001	8	view →
LSCC	DFS	Tertile	II,III,IV	0.826	1.000	.011	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ODF2L–HNSC (DFS)

Open the HNSC breakdown →