ODF1

Across TCGA patient cohorts, ODF1 mutation is significantly associated with the RNA expression of many other genes, with 1,041 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ODF1-associated genes across cancer lineages are RNU6-1174P, IGHD5-12, and HDHD5. Each is linked with ODF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ODF1-to-partner and partner-to-ODF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1174P grouped by ODF1-low versus ODF1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ODF1→partner) and Y-score (partner→ODF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-1174P →	+0.714	+5.554	<.001	.004	3	2
READ	IGHD5-12 →	+1.742	+5.421	<.001	.005	3	2
UCEC	HDHD5 →	+0.519	+3.609	.003	.001	3	2
BLCA	MIR561 →	+0.620	+5.064	<.001	.001	3	2
UCEC	VDAC1 →	+0.517	+2.823	.001	.001	3	2
UCEC	GOLGA2P7 →	+0.376	+3.361	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,041 associations by consensus.

RNU6-1174P by ODF1 expression — LUAD

Explore this box plot interactively →