ODCP

Across TCGA pan-cancer cohorts, ODCP RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of ODCP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ODCP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ODCP is over-expressed in tumor.

KIRP, HNSC, and KICH are the cancer types where ODCP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ODCP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Female	All	+0.409	<.001	11	view →
HNSC	Male	III,IV	+0.311	<.001	11	view →
KICH	All	II,III,IV	+0.169	.002	7	view →
BLCA	All	All	+0.391	.010	6	view →
UCEC	All	III,IV	+0.383	<.001	6	view →
BRCA	All	II,III,IV	+0.257	<.001	6	view →
LUSC	All	All	+0.228	<.001	5	view →
STAD	All	II,III,IV	+0.256	.017	4	view →
CHOL	All	All	+0.471	<.001	2	view →
LUAD	All	All	+0.265	.020	2	view →
READ	All	All	+0.216	.014	2	view →
COAD	All	All	+0.109	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

ODCP–KIRP

Open the KIRP breakdown →