ODC1-DT

Across TCGA pan-cancer cohorts, ODC1-DT RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ODC1-DT data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ODC1-DT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ODC1-DT expression acts as an unfavorable survival marker, although some lineages such as LGG and SKCM show a favorable association.

KIRC, ACC, and UCEC are the cancer types where ODC1-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.553	0.734	.001	95	view →
ACC	DFS	Tertile	All	0.505	0.788	.002	47	view →
UCEC	DFS	Quartile	All	0.530	0.826	<.001	40	view →
LGG	DFS	Median	All	0.484	0.315	<.001	38	view →
THYM	DFS	Quartile	II,III,IV	0.188	0.914	<.001	26	view →
SKCM	DFS	Quartile	All	0.683	0.514	.002	26	view →
UCS	OS	Quartile	III,IV	0.676	0.191	.004	24	view →
KICH	OS	Median	All	0.695	1.000	.004	22	view →
COAD	OS	Quartile	All	0.724	0.900	.005	19	view →
LIHC	DFS	Tertile	All	0.463	0.602	.007	19	view →
PAAD	OS	Tertile	All	0.585	0.265	.011	18	view →
HNSC	DFS	Median	IV	0.713	0.567	.005	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ODC1-DT–KIRC (DFS)

Open the KIRC breakdown →