ODAPH

Across TCGA cell cohorts, ODAPH RNA expression is significantly associated with the go_rna of many other GO terms, with 2,795 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ODAPH-associated GO terms across cancer lineages are Regulation of protein localization to mitochondrion, Regulation of proteolysis, and Regulation of enamel mineralization. Each is linked with ODAPH in more than 9 cancer types. Because this analysis shows association rather than direction, both ODAPH-to-partner and partner-to-ODAPH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to mitochondrion grouped by ODAPH-low versus ODAPH-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ODAPH→partner) and Y-score (partner→ODAPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of protein localization to mitochondrion →	+0.098	+0.164	<.001	<.001	3	10
OESOPHAGUS	Regulation of proteolysis →	+0.094	+0.505	.002	.003	3	10
KIDNEY	Regulation of enamel mineralization →	-0.282	-1.637	<.001	<.001	3	10
KIDNEY	Positive regulation of enamel mineralization →	-0.273	-1.712	<.001	<.001	3	10
OESOPHAGUS	Blood coagulation, intrinsic pathway →	+0.377	+0.445	<.001	.005	3	10
LUNG_NSCLC_LUSC	Regulation of angiogenesis →	+0.080	+0.697	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,795 associations by consensus.

Regulation of protein localization to mitochondrion by ODAPH expression — LARGE_INTESTINE

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