ODAPH

Across TCGA cell cohorts, ODAPH mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ODAPH-associated genes across cancer lineages are GSG1L2 and C5orf67. Each is linked with ODAPH in more than 1 cancer types. Because this analysis shows association rather than direction, both ODAPH-to-partner and partner-to-ODAPH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSG1L2 grouped by ODAPH-low versus ODAPH-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ODAPH→partner) and Y-score (partner→ODAPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GSG1L2 →	+0.043	+4.969	<.001	.003	3	1
BLOOD_Leukemia	C5orf67 →	+0.128	+4.409	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GSG1L2 by ODAPH expression — BLOOD_Leukemia

Explore this box plot interactively →