ODAM

Across TCGA patient cohorts, ODAM mutation is significantly associated with the RNA expression of many other genes, with 186 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ODAM-associated genes across cancer lineages are RNU1-33P, MIR516A1, and MIR4659A. Each is linked with ODAM in more than 1 cancer types. Because this analysis shows association rather than direction, both ODAM-to-partner and partner-to-ODAM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-33P grouped by ODAM-low versus ODAM-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ODAM→partner) and Y-score (partner→ODAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU1-33P →	+0.286	+5.018	<.001	.004	3	2
BLCA	MIR516A1 →	+0.649	+4.899	<.001	.005	3	2
HNSC	MIR4659A →	+0.501	+4.761	<.001	.001	3	2
UCEC	EIF1P2 →	+0.368	+2.715	<.001	.003	3	2
BLCA	RCC2P2 →	+0.046	+6.040	<.001	.001	3	2
BLCA	RNU7-54P →	+0.357	+4.899	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 186 associations by consensus.

RNU1-33P by ODAM expression — BLCA

Explore this box plot interactively →