OCSTAMP

Across TCGA patient cohorts, OCSTAMP protein abundance is significantly associated with the RNA expression of many other genes, with 582 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible OCSTAMP-associated genes across cancer lineages are KATNAL1, MYH14, and FSCN3. Each is linked with OCSTAMP in more than 1 cancer types. Because this analysis shows association rather than direction, both OCSTAMP-to-partner and partner-to-OCSTAMP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OCSTAMP versus KATNAL1 in LSCC, with a Pearson correlation of -0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OCSTAMP→partner) and Y-score (partner→OCSTAMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KATNAL1 →	-0.812	-2.308	<.001	<.001	3	1
LSCC	MYH14 →	+1.044	+2.060	.008	.007	3	1
LSCC	FSCN3 →	-0.194	-2.556	.006	<.001	3	1
LSCC	HSPA8 →	-0.689	-2.514	<.001	<.001	3	1
LSCC	PANX1 →	-0.760	-2.207	.005	.005	3	1
LSCC	STX2 →	-0.761	-2.161	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 582 associations by consensus.

OCSTAMP vs KATNAL1 — LSCC

Explore this scatter interactively →