OCSTAMP

Across TCGA cell cohorts, OCSTAMP RNA expression is significantly associated with the go_rna of many other GO terms, with 378 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OCSTAMP-associated GO terms across cancer lineages are Establishment of protein localization to endoplasmic reticulum, Regulation of D-glucose import across plasma membrane, and Interleukin-1-mediated signaling pathway. Each is linked with OCSTAMP in more than 2 cancer types. Because this analysis shows association rather than direction, both OCSTAMP-to-partner and partner-to-OCSTAMP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to endoplasmic reticulum grouped by OCSTAMP-low versus OCSTAMP-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OCSTAMP→partner) and Y-score (partner→OCSTAMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Establishment of protein localization to endoplasmic reticulum →	+0.040	+0.372	<.001	.009	3	3
LUNG_SCLC	Regulation of D-glucose import across plasma membrane →	+0.083	+0.021	.001	.009	3	3
LUNG_SCLC	Interleukin-1-mediated signaling pathway →	+0.090	+0.017	<.001	.002	3	3
SKIN	Metanephric mesenchyme development →	+0.127	+0.012	.007	.006	3	3
SKIN	Sialylation →	+0.120	+0.008	.001	.007	3	3
LUNG_NSCLC_LUAD	Toll-like receptor 4 signaling pathway →	+0.048	+0.005	<.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 378 associations by consensus.

Establishment of protein localization to endoplasmic reticulum by OCSTAMP expression — BLOOD_Leukemia

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