OCM

Across TCGA cell cohorts, OCM RNA expression is significantly associated with the go_rna of many other GO terms, with 1,565 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible OCM-associated GO terms across cancer lineages are Astrocyte activation, Negative regulation of NK T cell activation, and G2/M transition of mitotic cell cycle. Each is linked with OCM in more than 4 cancer types. Because this analysis shows association rather than direction, both OCM-to-partner and partner-to-OCM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Astrocyte activation grouped by OCM-low versus OCM-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OCM→partner) and Y-score (partner→OCM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Astrocyte activation →	+0.099	+0.097	.001	.004	3	5
SOFT_TISSUE	Negative regulation of NK T cell activation →	+0.402	+0.071	.003	<.001	3	5
OESOPHAGUS	G2/M transition of mitotic cell cycle →	-0.085	-0.118	.004	.009	3	5
BLOOD_Myeloma	Putrescine biosynthetic process from arginine →	-0.182	-0.082	<.001	.007	3	5
OESOPHAGUS	Negative regulation of motile cilium assembly →	+0.074	+0.093	.001	.005	3	5
OESOPHAGUS	Meiotic chromosome segregation →	-0.115	-0.091	.002	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,565 associations by consensus.

Astrocyte activation by OCM expression — BLOOD_Leukemia

Explore this box plot interactively →