Across TCGA patient cohorts, OCLN mutation is significantly associated with the RNA expression of many other genes, with 2,147 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OCLN-associated genes across cancer lineages are RNA5SP164, SNRPGP17, and LINC01492. Each is linked with OCLN in more than 2 cancer types. Because this analysis shows association rather than direction, both OCLN-to-partner and partner-to-OCLN results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OCLN→partner) and Y-score (partner→OCLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP164 →	+0.122	+4.360	<.001	.004	3	3
SKCM	SNRPGP17 →	+0.294	+4.374	<.001	.001	3	2
UCEC	LINC01492 →	+0.064	+2.064	.001	.008	3	2
UCEC	AKIRIN1P2 →	+0.224	+2.289	.001	.003	3	2
UCEC	RNA5SP436 →	+0.408	+2.937	<.001	.009	3	2
SKCM	LINC00901 →	+0.025	+4.513	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,147 associations by consensus.

Exploration

OCLN survival (RNA) · tumor vs normal (RNA) · all OCLN data types