OCEL1

Across TCGA pan-cancer cohorts, OCEL1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated OCEL1 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher OCEL1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated OCEL1 expression acts as an unfavorable survival marker, although some lineages such as GBM and CCRCC show a favorable association.

GBM, CCRCC, and LSCC are the cancer types where OCEL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Tertile	All	0.838	0.592	.013	15	view →
CCRCC	DFS	Tertile	All	1.000	0.616	.007	10	view →
LSCC	DFS	Median	All	0.998	0.887	.007	7	view →
LUAD	OS	Median	II,III,IV	0.847	0.449	.020	4	view →
PDAC	DFS	Tertile	III,IV	1.000	0.316	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

OCEL1–GBM (OS)

Open the GBM breakdown →