OCEL1

Across TCGA pan-cancer cohorts, OCEL1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of OCEL1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where OCEL1 RNA is repressed in tumor relative to normal tissue. In most cancer types OCEL1 is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.

COAD, THCA, and KIRC are the cancer types where OCEL1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OCEL1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	−1.205	<.001	10	view →
THCA	Male	III,IV	−0.727	<.001	9	view →
KIRC	Male	III,IV	+0.359	<.001	8	view →
LUSC	Female	All	−0.927	<.001	7	view →
READ	All	All	−0.818	<.001	7	view →
KICH	All	II,III,IV	−0.767	<.001	7	view →
LUAD	Male	All	−0.583	<.001	5	view →
LIHC	All	II,III,IV	+0.449	.003	4	view →
BRCA	All	III,IV	+0.420	.001	2	view →
PAAD	All	All	+0.392	.047	2	view →
CHOL	All	All	−0.714	.010	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

OCEL1–COAD

Open the COAD breakdown →