OBP2B

Across TCGA patient cohorts, OBP2B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,894 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible OBP2B-associated GO terms across cancer lineages are Protein stabilization, Positive regulation of DNA repair, and Regulation of stem cell differentiation. Each is linked with OBP2B in more than 11 cancer types. Because this analysis shows association rather than direction, both OBP2B-to-partner and partner-to-OBP2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein stabilization grouped by OBP2B-low versus OBP2B-high in KIRC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OBP2B→partner) and Y-score (partner→OBP2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Protein stabilization →	+0.035	+0.152	<.001	<.001	3	12
KIRC	Positive regulation of DNA repair →	+0.034	+0.175	<.001	<.001	3	11
STAD	Regulation of stem cell differentiation →	+0.083	+0.351	<.001	<.001	1	12
KIRC	Base-excision repair, gap-filling →	+0.038	+0.134	<.001	<.001	3	10
KIRC	Regulation of DNA-templated transcription elongation →	+0.037	+0.139	<.001	<.001	3	10
KIRC	Hematopoietic stem cell homeostasis →	+0.039	+0.121	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,894 associations by consensus.

Protein stabilization by OBP2B expression — KIRC

Explore this box plot interactively →