OBP2B

Across TCGA pan-cancer cohorts, OBP2B RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated OBP2B data layer compared with 4 for mutation status.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher OBP2B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OBP2B expression acts as an unfavorable survival marker, although some lineages such as LAML and UCEC show a favorable association.

UCS, KICH, and KIRC are the cancer types where OBP2B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	All	0.245	0.684	<.001	108	view →
KICH	DFS	Quartile	II,III,IV	0.401	0.943	<.001	47	view →
KIRC	DFS	Median	IV	0.232	0.655	<.001	40	view →
DLBC	DFS	Tertile	All	0.373	0.835	.009	36	view →
LAML	DFS	Tertile	All	0.685	0.292	.010	30	view →
UCEC	DFS	Median	IV	0.951	0.531	.008	26	view →
OV	OS	Tertile	III,IV	0.647	0.731	.018	22	view →
THCA	DFS	Median	III,IV	0.544	0.828	.008	16	view →
STAD	DFS	Tertile	II,III,IV	0.673	0.544	.029	16	view →
SARC	DFS	Quartile	All	0.434	0.644	.018	13	view →
LGG	DFS	Tertile	All	0.725	0.859	<.001	11	view →
ESCA	DFS	Median	All	0.404	0.585	.004	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

OBP2B–UCS (DFS)

Open the UCS breakdown →