OBP2B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OBP2B protein abundance is significantly associated with the RNA expression of many other genes, with 412 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OBP2B-associated genes across cancer lineages are XBP1, SAMM50, and PLEK2. Each is linked with OBP2B in more than 1 cancer types. Because this analysis shows association rather than direction, both OBP2B-to-partner and partner-to-OBP2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OBP2B versus XBP1 in UCEC, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OBP2B→partner) and Y-score (partner→OBP2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECXBP1 →+1.750+2.593<.001.00631
UCECSAMM50 →+0.721+2.593<.001.00631
UCECPLEK2 →+1.183+3.739.001.00131
UCECSEC23B →+1.029+3.646<.001.00331
UCECKCND1 →-1.150-2.594.001.00631
UCECRBM3 →+0.752+2.594.006.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 412 associations by consensus.

OBP2B vs XBP1 — UCEC

Per-sample scatter of OBP2B vs XBP1 in UCEC (Pearson r = 0.70).

Explore this scatter interactively →

Exploration