OBP2B

Across TCGA patient cohorts, OBP2B mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OBP2B-associated genes across cancer lineages are mv Endothelial cells, pDC, and lymphatic Endothelial cells. Each is linked with OBP2B in more than 1 cancer types. Because this analysis shows association rather than direction, both OBP2B-to-partner and partner-to-OBP2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mv Endothelial cells grouped by OBP2B-low versus OBP2B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OBP2B→partner) and Y-score (partner→OBP2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mv Endothelial cells →	-0.026	-3.000	.031	.036	3	1
UCEC	pDC →	+0.076	+3.032	.001	.018	3	1
UCEC	lymphatic Endothelial cells →	-0.026	-2.268	.027	.036	2	1
UCEC	Endothelial cells →	-0.045	-3.416	.017	.005	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

mv Endothelial cells by OBP2B expression — UCEC

Explore this box plot interactively →