OAZ1

Across TCGA cell cohorts, OAZ1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,474 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OAZ1-associated GO terms across cancer lineages are Positive regulation of anaphase-promoting complex-dependent catabolic process, Cytoplasm protein quality control, and Energy coupled proton transmembrane transport, against electrochemical gradient. Each is linked with OAZ1 in more than 11 cancer types. Because this analysis shows association rather than direction, both OAZ1-to-partner and partner-to-OAZ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of anaphase-promoting complex-dependent catabolic process grouped by OAZ1-low versus OAZ1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OAZ1→partner) and Y-score (partner→OAZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.120	+0.501	<.001	<.001	3	12
BLOOD_Leukemia	Cytoplasm protein quality control →	+0.105	+0.571	<.001	<.001	3	11
BONE	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.082	+0.477	.005	.005	2	11
BONE	Electron transport coupled proton transport →	+0.082	+0.477	.005	.005	2	11
LUNG_SCLC	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.134	+0.853	<.001	<.001	3	10
BONE	Cytoplasm protein quality control by the ubiquitin-proteasome system →	+0.135	+0.494	.007	.007	1	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,474 associations by consensus.

Positive regulation of anaphase-promoting complex-dependent catabolic process by OAZ1 expression — LUNG_SCLC

Explore this box plot interactively →