OAZ1

Across TCGA pan-cancer cohorts, OAZ1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated OAZ1 data layer compared with 2 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher OAZ1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OAZ1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and CESC show a favorable association.

ACC, SKCM, and LIHC are the cancer types where OAZ1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.247	0.652	<.001	87	view →
SKCM	OS	Tertile	All	0.844	0.709	<.001	52	view →
LIHC	OS	Median	All	0.416	0.597	<.001	48	view →
LAML	DFS	Tertile	All	0.357	0.679	<.001	48	view →
LGG	OS	Median	All	0.331	0.563	<.001	47	view →
KICH	DFS	Tertile	III,IV	0.059	1.000	.002	45	view →
CESC	DFS	Median	II,III,IV	0.642	0.363	<.001	44	view →
CHOL	OS	Tertile	II,III,IV	0.957	0.221	<.001	34	view →
READ	OS	Median	IV	0.492	0.873	.015	19	view →
LUSC	DFS	Tertile	All	0.438	0.282	.020	12	view →
STAD	OS	Tertile	III,IV	0.745	0.555	.023	12	view →
DLBC	DFS	Median	III,IV	0.140	0.917	.010	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

OAZ1–ACC (DFS)

Open the ACC breakdown →