OAT

Across TCGA patient cohorts, OAT protein abundance is significantly associated with the RNA expression of many other genes, with 8,475 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible OAT-associated genes across cancer lineages are LHPP, DOCK8, and GPR65. Each is linked with OAT in more than 4 cancer types. Because this analysis shows association rather than direction, both OAT-to-partner and partner-to-OAT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OAT versus LHPP in UCEC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OAT→partner) and Y-score (partner→OAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LHPP →	+0.565	+0.603	<.001	<.001	3	5
BRCA	DOCK8 →	-0.638	-0.470	<.001	.004	3	5
HNSC	GPR65 →	-0.612	-0.431	<.001	<.001	3	5
BRCA	IGSF6 →	-0.665	-0.535	<.001	.001	3	5
HNSC	P2RY13 →	-0.737	-0.419	<.001	<.001	3	5
LUAD	LRRK2 →	-1.163	-0.711	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,475 associations by consensus.

OAT vs LHPP — UCEC

Explore this scatter interactively →