OAS3

Across TCGA patient cohorts, OAS3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,411 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible OAS3-associated proteins across cancer lineages are DDX58, EIF2AK2, and HELZ2. Each is linked with OAS3 in more than 9 cancer types. Because this analysis shows association rather than direction, both OAS3-to-partner and partner-to-OAS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OAS3 versus DDX58 in OV, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OAS3→partner) and Y-score (partner→OAS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DDX58 →	+0.802	+1.535	<.001	<.001	3	10
LSCC	EIF2AK2 →	+0.429	+1.311	<.001	<.001	3	10
LSCC	HELZ2 →	+0.505	+1.290	<.001	<.001	3	10
HNSC	IFIT1 →	+1.040	+1.138	<.001	<.001	3	10
HNSC	IFIT3 →	+1.226	+1.179	<.001	<.001	3	10
LSCC	ISG15 →	+0.949	+1.371	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,411 associations by consensus.

OAS3 vs DDX58 — OV

Explore this scatter interactively →