OAS3

Across TCGA patient cohorts, OAS3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,872 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible OAS3-associated genes across cancer lineages are DDX58, OAS2, and CMPK2. Each is linked with OAS3 in more than 9 cancer types. Because this analysis shows association rather than direction, both OAS3-to-partner and partner-to-OAS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OAS3 versus DDX58 in OV, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OAS3→partner) and Y-score (partner→OAS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DDX58 →	+1.211	+0.785	<.001	<.001	3	10
LSCC	OAS2 →	+1.633	+0.859	<.001	<.001	3	10
OV	CMPK2 →	+1.482	+0.869	<.001	<.001	3	10
BRCA	OASL →	+1.832	+0.777	<.001	<.001	3	10
PDAC	IFI44L →	+1.848	+0.886	<.001	<.001	3	10
OV	IFI44 →	+1.482	+0.815	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,872 associations by consensus.

OAS3 vs DDX58 — OV

Explore this scatter interactively →