Across TCGA patient cohorts, OAF RNA expression is significantly associated with the protein abundance of many other proteins, with 11,652 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OAF-associated proteins across cancer lineages are MAP1A, HIC1_S237, and PXN. Each is linked with OAF in more than 6 cancer types. Because this analysis shows association rather than direction, both OAF-to-partner and partner-to-OAF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OAF→partner) and Y-score (partner→OAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MAP1A →	+0.449	+0.463	<.001	<.001	3	7
OV	HIC1_S237 →	+0.949	+0.790	.001	.005	3	6
GBM	PXN →	+0.490	+0.929	<.001	<.001	3	5
GBM	COL3A1 →	+0.763	+0.781	<.001	<.001	3	5
GBM	DAB2 →	+0.690	+0.888	<.001	<.001	2	6
UCEC	ILK →	+0.496	+0.571	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,652 associations by consensus.

Exploration

OAF survival (RNA) · tumor vs normal (RNA) · all OAF data types