Across TCGA patient cohorts, NYNRIN mutation is significantly associated with the RNA expression of many other genes, with 4,879 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NYNRIN-associated genes across cancer lineages are IER3IP1, HSPA9, and ZWINT. Each is linked with NYNRIN in more than 5 cancer types. Because this analysis shows association rather than direction, both NYNRIN-to-partner and partner-to-NYNRIN results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NYNRIN→partner) and Y-score (partner→NYNRIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	IER3IP1 →	+0.588	+3.526	<.001	.002	3	6
STAD	HSPA9 →	+0.644	+3.459	<.001	.005	3	5
UCEC	ZWINT →	+0.603	+1.440	<.001	<.001	3	5
COAD	PSMC3IP →	+0.427	+2.525	.003	.009	3	5
STAD	RCC1 →	+0.643	+3.334	.009	.005	3	5
COAD	EXOSC9 →	+0.442	+2.920	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,879 associations by consensus.

Exploration

NYNRIN survival (RNA) · tumor vs normal (RNA) · all NYNRIN data types