NXT1-AS1

Across TCGA pan-cancer cohorts, NXT1-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated NXT1-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher NXT1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NXT1-AS1 expression acts as an unfavorable survival marker, although some lineages such as READ and UCS show a favorable association.

MESO, KIRP, and ACC are the cancer types where NXT1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.427	0.723	<.001	108	view →
KIRP	OS	Quartile	III,IV	0.105	0.709	<.001	81	view →
ACC	DFS	Tertile	All	0.497	0.852	<.001	56	view →
READ	OS	Median	II,III,IV	0.777	0.315	<.001	54	view →
CESC	DFS	Quartile	All	0.742	0.869	.005	36	view →
STAD	DFS	Tertile	II,III,IV	0.570	0.713	.015	25	view →
SARC	OS	Quartile	All	0.640	0.912	.001	23	view →
SKCM	DFS	Tertile	III,IV	0.324	0.752	<.001	19	view →
LUSC	DFS	Quartile	All	0.556	0.700	.014	15	view →
BLCA	DFS	Tertile	All	0.291	0.613	.002	12	view →
THCA	DFS	Quartile	III,IV	0.392	0.852	.007	11	view →
COAD	OS	Tertile	II,III,IV	0.806	0.923	.014	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

NXT1-AS1–MESO (OS)

Open the MESO breakdown →