NXPE4

Across TCGA patient cohorts, NXPE4 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,405 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NXPE4-associated proteins across cancer lineages are MYLK, TXNDC5, and JCHAIN. Each is linked with NXPE4 in more than 5 cancer types. Because this analysis shows association rather than direction, both NXPE4-to-partner and partner-to-NXPE4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NXPE4 versus MYLK in PDAC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NXPE4→partner) and Y-score (partner→NXPE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MYLK →	+0.476	+0.353	<.001	<.001	3	6
OV	TXNDC5 →	+0.635	+0.180	<.001	.001	3	6
LUAD	JCHAIN →	+0.747	+0.311	<.001	.001	3	6
CCRCC	LMOD1_S85 →	+0.715	+0.245	<.001	.006	3	6
HNSC	HNMT →	+0.453	+0.353	<.001	<.001	3	5
LUAD	HSP90AA1_S453 →	-0.459	-0.417	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,405 associations by consensus.

NXPE4 vs MYLK — PDAC

Explore this scatter interactively →