NXPE4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NXPE4 protein abundance is significantly associated with the RNA expression of many other genes, with 593 significant associations in total. COAD shows the largest number of these associations.

The most reproducible NXPE4-associated genes across cancer lineages are LGALS2, PACSIN2, and RIOK3. Each is linked with NXPE4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NXPE4-to-partner and partner-to-NXPE4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NXPE4 versus LGALS2 in COAD, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NXPE4→partner) and Y-score (partner→NXPE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADLGALS2 →+1.058+0.437.001.00231
COADPACSIN2 →+0.349+0.435.007.00531
COADRIOK3 →+0.629+0.631<.001<.00131
COADPHKB →+0.306+0.481<.001<.00131
COADFAH →-0.596-0.646<.001.00131
COADCA2 →+1.470+0.502.004.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 593 associations by consensus.

NXPE4 vs LGALS2 — COAD

Per-sample scatter of NXPE4 vs LGALS2 in COAD (Pearson r = 0.42).

Explore this scatter interactively →

Exploration