NXPE4

Across TCGA cell cohorts, NXPE4 RNA expression is significantly associated with the go_rna of many other GO terms, with 374 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NXPE4-associated GO terms across cancer lineages are Promoter clearance during DNA-templated transcription, RNA polymerase II promoter clearance, and Negative regulation of G protein-coupled receptor signaling pathway. Each is linked with NXPE4 in more than 3 cancer types. Because this analysis shows association rather than direction, both NXPE4-to-partner and partner-to-NXPE4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Promoter clearance during DNA-templated transcription grouped by NXPE4-low versus NXPE4-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NXPE4→partner) and Y-score (partner→NXPE4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Promoter clearance during DNA-templated transcription →	+0.076	+0.006	<.001	.001	3	4
BLOOD_Leukemia	RNA polymerase II promoter clearance →	+0.076	+0.006	<.001	.001	3	4
BLOOD_Lymphoma	Negative regulation of G protein-coupled receptor signaling pathway →	-0.054	-0.006	.001	.005	3	3
BLOOD_Lymphoma	NLS-bearing protein import into nucleus →	+0.064	+0.008	.009	.009	3	3
BLOOD_Leukemia	Protein import into peroxisome matrix →	+0.037	+0.007	.009	.004	3	3
BLOOD_Leukemia	Protein transmembrane import into intracellular organelle →	+0.037	+0.007	.009	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 374 associations by consensus.

Promoter clearance during DNA-templated transcription by NXPE4 expression — BLOOD_Leukemia

Explore this box plot interactively →