NXN

Across TCGA patient cohorts, NXN mutation is significantly associated with the RNA expression of many other genes, with 1,944 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NXN-associated genes across cancer lineages are RN7SL93P, MIR8082, and OXSM. Each is linked with NXN in more than 1 cancer types. Because this analysis shows association rather than direction, both NXN-to-partner and partner-to-NXN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL93P grouped by NXN-low versus NXN-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NXN→partner) and Y-score (partner→NXN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	RN7SL93P →	+0.702	+6.453	<.001	.001	3	2
UCEC	MIR8082 →	+0.270	+2.183	.005	.009	3	2
UCEC	OXSM →	+0.398	+2.332	.001	.003	3	2
UCEC	NUDCD2 →	+0.520	+3.021	.002	<.001	3	2
UCEC	UBE2T →	+0.697	+2.364	.003	.003	3	2
UCEC	TMED2 →	+0.543	+3.332	.009	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,944 associations by consensus.

RN7SL93P by NXN expression — PRAD

Explore this box plot interactively →