NXF2B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NXF2B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,085 significant associations in total. OV shows the largest number of these associations.

The most reproducible NXF2B-associated GO terms across cancer lineages are Microtubule-based transport, Transport along microtubule, and Positive regulation of organelle assembly. Each is linked with NXF2B in more than 14 cancer types. Because this analysis shows association rather than direction, both NXF2B-to-partner and partner-to-NXF2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule-based transport grouped by NXF2B-low versus NXF2B-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NXF2B→partner) and Y-score (partner→NXF2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SCLCMicrotubule-based transport →+0.047+0.747<.001<.001315
SCLCTransport along microtubule →+0.049+0.728<.001<.001314
SCLCPositive regulation of organelle assembly →+0.056+0.533.004.002313
SCLCRegulation of protein localization to cilium →+0.111+0.677<.001<.001312
SCLCPositive regulation of double-strand break repair →+0.061+0.574<.001<.001312
SCLCProtein-containing complex localization →+0.047+0.525.002.001213
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,085 associations by consensus.

Microtubule-based transport by NXF2B expression — SCLC

Box plot of Microtubule-based transport in NXF2B-low vs NXF2B-high samples in SCLC.

Explore this box plot interactively →

Exploration