NXF2B

Across TCGA cell cohorts, NXF2B RNA expression is significantly associated with the go_rna of many other GO terms, with 480 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible NXF2B-associated GO terms across cancer lineages are RNA localization, Negative regulation of myoblast fusion, and Heterochromatin formation. Each is linked with NXF2B in more than 4 cancer types. Because this analysis shows association rather than direction, both NXF2B-to-partner and partner-to-NXF2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA localization grouped by NXF2B-low versus NXF2B-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NXF2B→partner) and Y-score (partner→NXF2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	RNA localization →	+0.060	+0.865	.007	.005	3	5
SKIN	Negative regulation of myoblast fusion →	+0.046	+0.390	.008	.005	3	4
CNS	Heterochromatin formation →	+0.029	+0.651	.002	.004	3	4
CNS	Heterochromatin organization →	+0.028	+0.678	.002	.002	3	4
CNS	RNA surveillance →	+0.031	+0.818	.009	.005	2	5
LUNG_SCLC	Transport along microtubule →	+0.061	+1.143	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 480 associations by consensus.

RNA localization by NXF2B expression — LUNG_SCLC

Explore this box plot interactively →